US10307394B2 – June 4, 2019 – Dosage delivery film

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Inventors :

Sergey Y. Chistov

Owner :

SPARTAK LLC, NEW JERSEY

Application Number :

US16058669

Document Number :

US10307394B2

Priority Date :

August 8, 2018

Filing Date :

August 8, 2018

Date of Grant/ Publication :

June 4, 2019

Class :

; A61K31 / 352; A61K31 / 05; A61K47 / 40; A61K9 / 107; A61K31 / 353; A61K9 / 70; A61K31 / 343; A61K9 / 00; A61K47 / 06; A61K47 / 08; A61K47 / 10; A61K47 / 26

Abstract

A dosage delivery film composition containing a botanical drug substance formable into a bioerodible dosage delivery film, the dosage delivery film composition including: (i) one or more of: a polymer, a plasticizer, a defoamer, or an antioxidant; (ii) a cannabinoid-cyclodextrin-terpene complex or a cannabinoid-terpene-surfactant micelle, and (iii) optionally, one or more of: a taste mask, a vasodilator, or a lipophilic vehicle to transport the botanical drug substance across the mucous membrane.

Claim(s)

1. A composition comprising: a cannabinoid-cyclodextrin complex including a cannabinoid associated with a ?-cyclodextrin; and a cannabinoid micelle admixed with said cannabinoid-?-cyclodextrin complex, said cannabinoid micelle consisting essentially of cannabinoid having an outer hydrophilic surfactant shell.

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