US10328111B2 – June 25, 2019 – Water-soluble phytocannabinoid formulations

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Inventors :

Eric Kuhrts

Owner :

A61K36 / 185; A23L2 / 52; A61K9 / 00; A61K9 / 107; A61K9 / 20; A61K9 / 48; A61K31 / 05; A61K31 / 352; A61K36 / 752; A61K47 / 44

Application Number :


Document Number :


Priority Date :

August 14, 2018

Filing Date :

August 14, 2018

Date of Grant/ Publication :

June 25, 2019

Class :



Methods and formulations for increasing the water solubility and/or bioavailability of a phytocannabinoid compound is disclosed herein. In one example, a water-soluble phytocannabinoid formulation can comprise a phytocannabinoid; a non-ionic surfactant; and optionally, water. The weight ratio of phytocannabinoid content to non-ionic surfactant can be from 1:10,000 to 1:5.


1. A phytocannabinoid emulsion formulation, comprising: a solution including water at a concentration greater than about 50 wt % in the formulation and propylene glycol; a phytocannabinoid oil including a phytocannabinoid compound; and a non-ionic surfactant, wherein the weight ratio of phytocannabinoid compound content to non-ionic surfactant is from 1:10,000 to 1:5, and wherein the phytocannabinoid oil and the non-ionic surfactant form particles of undissolved lipophilic compound within the solution that are not visible to the naked eye.


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